Published: Jan 1, 2018
Converted to Gold OA:
DOI: 10.4018/JNN.2018010101
Volume 3
Research Article
Sabna Kotta, Navneet Sharma, Prateek Raturi, Mohd Aleem, Rakesh Kumar Sharma
Currently, the concept of lipid-based drug delivery systems has gained much interest because of their capability to deliver drugs which dissolve sparingly in water or insoluble in nature. Several...
Show More
Currently, the concept of lipid-based drug delivery systems has gained much interest because of their capability to deliver drugs which dissolve sparingly in water or insoluble in nature. Several methods of lipid-based drug delivery exist, and each method has its own advantages as well as limitations. The primary objective of the formulation development is to improve the bioavailability of the drug. The nano-sized lipid-based drug delivery systems have enough potential to do so. This article addresses the various barriers to the transportation of drugs through certain routes and also the common excipients which used to develop the lipid-based drug delivery systems. It provides a thorough overview of the lipid formulation classification scheme (LFCS) and also deals with several formulation & evaluation aspects of lipid-based drug delivery system. Further, it focuses on the formulations which are already available in the market and their regulatory concerns, respectively.
Content Forthcoming
Add to Your Personal Library: Article
Cite Article
Cite Article
MLA
Kotta, Sabna, et al. "Exploring Novel Strategies for Lipid-Based Drug Delivery." JNN vol.3, no.1 2018: pp.1-22. http://doi.org/10.4018/JNN.2018010101
APA
Kotta, S., Sharma, N., Raturi, P., Aleem, M., & Sharma, R. K. (2018). Exploring Novel Strategies for Lipid-Based Drug Delivery. Journal of Nanotoxicology and Nanomedicine (JNN), 3(1), 1-22. http://doi.org/10.4018/JNN.2018010101
Chicago
Kotta, Sabna, et al. "Exploring Novel Strategies for Lipid-Based Drug Delivery," Journal of Nanotoxicology and Nanomedicine (JNN) 3, no.1: 1-22. http://doi.org/10.4018/JNN.2018010101
Export Reference
Published: Jan 1, 2018
Converted to Gold OA:
DOI: 10.4018/JNN.2018010102
Volume 3
Research Article
Rahul B Chavan, Nalini R Shastri
Multi-drug therapy involves the simultaneous or sequential administration of two or more drugs with similar or different mechanisms of action and is efficient in combating various ailments such as...
Show More
Multi-drug therapy involves the simultaneous or sequential administration of two or more drugs with similar or different mechanisms of action and is efficient in combating various ailments such as cancer, diabetes, and rheumatoid arthritis. It has emerged advantageous due to larger therapeutic benefits, an increase in patient compliance, lower administrative costs, and reduced number of prescriptions. In the recent past, the clinical success of the Novartis product Entresto (sacubitril, disodium valsartan and water) and Esteve product E-58425 (tramadol and celecoxib) has boosted the development of multi-drug . The present article is hence designed to provide an overview of different multicomponent addicts which provide option of combining the drugs at a supramolecular level (nano-sized level). Key features of multi-drug cocrystal, co-amorphous system and eutectics are described with major emphasis on screening tools, preparation methods, characterization techniques, biopharmaceutical aspects and scale up.
Content Forthcoming
Add to Your Personal Library: Article
Cite Article
Cite Article
MLA
Chavan, Rahul B., and Nalini R. Shastri. "Overview of Multicomponent Solid Forms." JNN vol.3, no.1 2018: pp.23-48. http://doi.org/10.4018/JNN.2018010102
APA
Chavan, R. B. & Shastri, N. R. (2018). Overview of Multicomponent Solid Forms. Journal of Nanotoxicology and Nanomedicine (JNN), 3(1), 23-48. http://doi.org/10.4018/JNN.2018010102
Chicago
Chavan, Rahul B., and Nalini R. Shastri. "Overview of Multicomponent Solid Forms," Journal of Nanotoxicology and Nanomedicine (JNN) 3, no.1: 23-48. http://doi.org/10.4018/JNN.2018010102
Export Reference
Published: Jan 1, 2018
Converted to Gold OA:
DOI: 10.4018/JNN.2018010103
Volume 3
Research Article
Anju Gupta, Poornima Kalyanram, Istvan Stadler
Riboflavin presents tremendous potential as a photosensitizing agent for photodynamic therapy (PDT) for treating microbial infection and cancer therapy. Encapsulation of riboflavin can improve its...
Show More
Riboflavin presents tremendous potential as a photosensitizing agent for photodynamic therapy (PDT) for treating microbial infection and cancer therapy. Encapsulation of riboflavin can improve its bioavailability and stability while making the clinical applications more efficient. The authors' detailed study on cellular inhibition of liposome encapsulated riboflavin-5-phosphate investigation, and the effect of unencapsulated riboflavin on liposome bilayers aims to improve the efficiency of cellular delivery of riboflavin. Nano-sized liposomes composed of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and cholesterol were used in this study. Cell studies demonstrate high inhibition rates for the lipsome-encapsualted high concentration riboflavin formulations in the presence of blue light, despite the lower encapsulation lading.
Content Forthcoming
Add to Your Personal Library: Article
Cite Article
Cite Article
MLA
Gupta, Anju, et al. "Interaction of Riboflavin-5-Phosphate With Liposome Bilayers." JNN vol.3, no.1 2018: pp.49-59. http://doi.org/10.4018/JNN.2018010103
APA
Gupta, A., Kalyanram, P., & Stadler, I. (2018). Interaction of Riboflavin-5-Phosphate With Liposome Bilayers. Journal of Nanotoxicology and Nanomedicine (JNN), 3(1), 49-59. http://doi.org/10.4018/JNN.2018010103
Chicago
Gupta, Anju, Poornima Kalyanram, and Istvan Stadler. "Interaction of Riboflavin-5-Phosphate With Liposome Bilayers," Journal of Nanotoxicology and Nanomedicine (JNN) 3, no.1: 49-59. http://doi.org/10.4018/JNN.2018010103
Export Reference
IGI Global Open Access Collection provides all of IGI Global’s open access content in one convenient location and user-friendly interface
that can easily searched or integrated into library discovery systems.
Browse IGI Global Open
Access Collection
Author Services Inquiries
For inquiries involving pre-submission concerns, please contact the Journal Development Division:
journaleditor@igi-global.comOpen Access Inquiries
For inquiries involving publishing costs, APCs, etc., please contact the Open Access Division:
openaccessadmin@igi-global.comProduction-Related Inquiries
For inquiries involving accepted manuscripts currently in production or post-production, please contact the Journal Production Division:
journalproofing@igi-global.comRights and Permissions Inquiries
For inquiries involving permissions, rights, and reuse, please contact the Intellectual Property & Contracts Division:
contracts@igi-global.comPublication-Related Inquiries
For inquiries involving journal publishing, please contact the Acquisitions Division:
acquisition@igi-global.comDiscoverability Inquiries
For inquiries involving sharing, promoting, and indexing of manuscripts, please contact the Citation Metrics & Indexing Division:
indexing@igi-global.com Editorial Office
701 E. Chocolate Ave.
Hershey, PA 17033, USA
717-533-8845 x100